One form of hereditary cataract can result when a single base mutation in
a particular region of the L-ferritin messenger RNA changes the way the
resultant molecule folds. The RNAbow cover image dramatically highlights the
structural differences that can occur after making a single substitution at base
22 (from U to G). Red arcs are unique to the folds in the typical sequence,
blue arcs are strengthened in the mutant, and black arcs undergo negligible
change.
The Science Executive Committee wishes to express its gratitude to the
extensive efforts of all the science departmental executive assistants in
preparing contributions for this publication.
Editor: Dr. Bryce
Babcock
This document is printed on recycled
paper.
Williams
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